مطالب

Aging is influenced by a wide range of biological processes, with increasing attention focused on physical exercise as an effective, non-pharmacological intervention to support healthy aging and extend lifespan. This review examines how exercise influences aging mechanisms by activating Forkhead Box O (FOXO) proteins—especially FOXO3, a critical regulator of oxidative stress resistance, metabolism, and cellular repair. By integrating evidence from both animal models and human studies, we explore how different types of physical activity, including endurance and resistance training, enhance FOXO signaling pathways that govern mitochondrial health, autophagy, and inflammation control. FOXO activation appears to play a central role in mitigating age-related diseases such as sarcopenia, cardiovascular disease, neurodegeneration, and cancer. While preclinical studies consistently demonstrate these protective effects, human data are more variable, highlighting the influence of age, sex, and intervention type. Understanding the molecular connection between exercise and FOXO activity can help develop targeted exercise recommendations to promote longevity and delay age-associated functional decline.

The current study adopted a mixed-method design approach to investigate the effect of the integration of the TPS strategy instruction into reading lessons on EFL students’ motivation to read. One hundred twenty Iranian intermediate EFL students (60 male and 60 female), studying English in a language institute in Iran, were selected and randomly assigned to an experimental group (N = 60) and a control group (N = 60). The experimental group received ten sessions of reading instruction based on the TPS-integrated reading strategy proposed by Baker and Westrup (2000) whereas the control groups received the same amount of instruction on the same materials based on the traditional direct instruction method. Then, the students’ reading motivations were measured using the revised version of the Motivation for Reading Questionnaire (MRQ) (Wigfield & Guthrie, 1997). Besides, the students’ attitudes toward the TPS-integrated reading strategy instruction were examined by conducting a semi-structured interview. The analysis of the quantitative data showed no significant difference between the experimental and control groups in terms of reading motivation. It was also revealed that the integration of the TPS strategy in the reading lessons affected neither the students’ intrinsic motivation nor their extrinsic motivation. However, the findings of the interview concluded that the majority of the participants had developed positive attitudes toward the TPS. Regarding the motivation for reading, however, the findings of the interview were mixed. Finally, the study suggested some practical implications for EFL classrooms.

The use of urban streets as an element of urban life is jeopardized today, particularly In rising metropolises such as Tehran, due to the rapid rise in automobile ownership, population expansion, ineffective transit systems, poor quality urban architecture, and other challenges. On the other hand, there are various potential to efficiently drive urban growth toward sustainability in an era of digitalization, artificial intelligence and the Internet of Things. It implemented that the use of new urban technologies is looking for methods and incentives to encourage today's citizens to walk more. This research attempts to address the question “does smartification of urban spaces significant impact on walkability”? This paper examines the effect of smartification defined as the incorporation of digital technologies and IOT solutions on walkability in urban spaces. By analyzing design of pedestrian path with various smart initiatives, such as gamification, pedestrian-friendly infrastructure, and digital solutions, this study seeks to understand how these innovations contribute to creating more walkable environments. This study used a quantitative approach to test its assumptions, and SPSS software and a questionnaire were used to examine the data that was gathered. Additionally, Friedman's test and the single population mean test (t-test) were employed to evaluate the research assumptions. The study's findings indicate that smart buildings can enhance pedestrian circulation in the studied location (Farahzadi Blvd., Shahrak Gharb). The findings suggest that smartification can significantly enhance walkability by improving safety, Social interaction, and pleasurability in user experience. Additionally, from the perspective of users, smartification has the most influence on the comfort factor that promotes walking.

La problématique de l'origine de la vie sur Terre est l'une des questions ontologiques les plus fondamentales tout au long de l'histoire humaine et a généralement été l'objet de controverses entre les scientifiques empiriques et les érudits religieux. L'objectif principal de cette recherche est d'examiner les points de vue des exégètes du Coran et des scientifiques des sciences empiriques sur le phénomène de la vie sur Terre. À cet égard, après avoir examiné les significations lexicales et techniques des mots vie, science empirique et exégèse scientifique, les opinions des exégètes musulmans sur l'origine de la vie sur Terre ont été examinées, les théories et les hypothèses les plus importantes et les plus célèbres des scientifiques des sciences empiriques sur ce sujet ont été discutées et analysées. La méthode de recherche utilisée dans cet article est descriptive et analytique ; c'est-à-dire que les données recueillies sont présentées en s'appuyant sur des preuves rationnelles et narratives et font l'objet d'une analyse, comparaison et d'une application. La méthode de collecte des données dans cette recherche est basée sur des sources bibliographiques. Les résultats de la recherche montrent que le Coran ne fait pas directement référence à la question de l'origine de la vie sur Terre ; mais il fournit des détails précis sur la création et l'origine des êtres humains. De même, un grand nombre des théories et des hypothèses présentées par les anciens et les scientifiques contemporains des sciences empiriques sur l'origine et l'apparition de la vie sur la planète Terre ne correspondent pas aux récits coraniques.

Background and Theoretical Foundations: Throughout history, humanity has always been involved in numerous crises, including war and bloodshed, and their undesirable consequences and effects. Establishing peace and resolving conflicts has always been of interest to scholars, and accordingly, two main views have been put forward in this regard under the headings of "the originality of peace" or "just war". Meanwhile, sea bandits or piracy, which have a very old history and are as old as the history of human domination of the sea, have become a serious threat to the security of international trade in recent years, since 2008, due to reasons such as changing the behavioral pattern of pirates who often take hostages and extort money. The crime of piracy is one of the first international crimes with global jurisdiction, and has always been the subject of discussion among scholars of various legal systems. One of the important issues in this regard is how to establish peace or a just war with this phenomenon. Methodology: In this research, which uses a descriptive and analytical method, piracy was studied in a comparative manner from the perspective of just war theory in Islamic jurisprudence and international law. The data collection tools in this qualitative research are the use of library resources and texts, and electronic journals, with a common approach in identifying and critiquing the research conducted. Findings: It shows that the Islamic legal system and international law have presented mostly similar and sometimes different views in this regard, but ultimately, both legal systems support the observance of ethical and humanitarian principles. Conclusion: The results show that today, the issue of war is an important issue and challenge that can only be accepted when it is accepted as a just challenge in the international arena. Therefore, considering the principles of international law and the actions of pirates, in many cases there are many similarities with the term war in Islamic jurisprudence, and their behavior and actions, which often lead to the deprivation of sea security, can be considered as war, but observing the principles of just war is both essential and of fundamental importance in the Islamic legal system.