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Purpose: Diabetes mellitus is the most common metabolic problem worldwide, which is associated with hyperglycemia and structural and functional disorders of the nervous system. The aim of the present study was to investigate the effect of endurance training on serum glucose levels, weight changes and Like Growth Factor 1 (IGF-1) protein expression in the hippocampus of diabetic rats. Method: For this study, the samples included 48 male Wistar rats (8 weeks old), which were divided into 4 groups: control (C), the diabetes control (DC), diabetes-training (DT) and exercise (T). In order to induce diabetes, streptozotocin injection was used. 5 sessions per week of endurance activity were performed for 6 weeks. 48 hours after the completion of the exercise program, hippocampal tissue was dissected and extracted. ELISA method and one-way variance test were used to analyze the data. Resalts: Based on the results, serum glucose levels decreased after six weeks of endurance training (p=0.001). The amount of IGF-1 in group DC was significantly lower compared to all groups DT, T, and C (P≤0.05). But the DT group had no significant difference with the C and T groups (P=0.210 and P=0.226, respectively). On the other hand, the amount of IGF-1 in group T was only significantly different from group D (P=0.001). The correlation between blood glucose and IGF-1 was significant (p=0.001, r=0.820). Conclusion: Diabetes reduces IGF-1 and hyperglycemia, but exercise moderates the effect of diabetes on IGF-1. Considering the appropriate duration of training and the correlation of this protein with blood glucose, maybe endurance training can reduce the negative effect of diabetes.

Employment is one of the most fundamental forms of human activity, the damages of which can cause job burnout and reduce quality of life. In recent years, dealing with this issue has been the main goal of most organizations. The present study aims to compare job burnout and quality of life among active and inactive clerks in one of Tehran universities. In the present causative comparative study, 100 clerks of the age range (mean and standard deviation 40.93 ±8.63) of the university which was chosen by access sampling. According to Sharkey's physical activity questionnaire, they were then divided into two active and inactive groups. Then, they filled out two Maslach job burnout and quality of life questionnaires. A multivariate variance analysis test was used with SPSS 20 for data analysis. The data and findings indicate that concerning job burnout and its subscales (Emotional Exhaustion, Depersonalization), physically inactive individuals had higher means; in contrast, people with more activity had higher means; also, physically active individuals showed higher mean scores in quality-of-life variable, in both physical health and mental health total scores and physical function, emotional wellbeing, social function, and general health subscales. Physically inactive individuals showed higher means concerning function disorder owing to physical health and function disorder owing to emotional health and pain. There was no significant difference concerning the subscale of energy/fatigue. Findings indicate that physical activity, as a strategy, improves the capacity of the clerks so they have a better quality of life and deal with job burnout. Thus, it is suggested that physical activity be used as a strategic plan to increase the clerks' efficiency.

Purpose: This study aimed to investigate the relationship between gut microbiome composition, athletic performance, and post-exercise recovery in endurance athletes following probiotic supplementation.  Method: In this randomized, double-blind, placebo-controlled study, 40 male endurance runners (age: 28.3 ± 5.2 years) were randomly assigned to either a probiotic (n=20) or placebo (n=20) group for 8 weeks. The probiotic group received a daily supplement containing a blend of Lactobacillus acidophilus, Bifidobacterium lactis, and Lactobacillus plantarum (20 billion CFU total). Fecal samples were collected before and after the intervention and analyzed using 16S rRNA gene sequencing. Athletic performance was assessed through VO2max testing and time to exhaustion. Recovery was evaluated by measuring delayed onset muscle soreness (DOMS) and creatine kinase (CK) levels. Results: The probiotic group showed a significant increase in gut microbial diversity (Shannon index: p<0.01) and relative abundance of beneficial bacteria such as Bifidobacterium and Lactobacillus (p<0.001). Significant improvements were observed in VO2max (4.7%, p<0.05) and time to exhaustion (7.2%, p<0.01) in the probiotic group compared to placebo. The probiotic group also demonstrated reduced DOMS (23%, p<0.05) and lower peak CK levels (18%, p<0.01) relative to the placebo group. Multiple regression analysis revealed that changes in Akkermansia muciniphila and Bifidobacterium abundances were significant predictors of performance improvement (R² = 0.68, p<0.001). Conclusion: This study provides evidence that gut microbiome modulation through probiotic supplementation can enhance athletic performance and accelerate post-exercise recovery in endurance runners. These findings suggest that targeted manipulation of the gut microbiome may be a novel strategy for improving sports performance and recovery.

Purpose: Osteoporosis is a multifactorial disease of the skeletal system and the main cause of fractures and death in elderly people, especially postmenopausal women. The purpose of this study was to investigate the effect of eight weeks of resistance training on some serum and metabolic markers of bone mass in postmenopausal women. Methods: 24 inactive postmenopausal women with an age range of 46-58 years participated in this study. Subjects were assigned to resistance training and control groups. Before and after the training period, weight, body mass index, alkaline phosphatase, calcium, serum phosphorus and bone density of lumbar vertebrae were measured (by Dexa method). The training protocol consisted of upper and lower body resistance training in 3 sets of 8 to 12 repetitions for 8 weeks and 3 sessions per week. Data were analyzed using SPSS software version 26 and independent t and paired t statistical tests. Results: The results of this research showed that the experimental group had a significant increase in the amount of alkaline phosphatase (p=0.041), serum calcium (p=0.035) and bone density of the lumbar vertebrae (p=0.11) and a significant decrease in weight compared to the control group. (p=0.035, and body mass index p=0.021). The results also showed no significant change in the amount of serum phosphorus (p=0.071). Conclusion: According to the findings of the present study, in order to maintain or prevent the decrease in bone density of postmenopausal women, resistance exercises can be recommended.

Background: Instrument Assisted Soft Tissue Mobilization (IASTM) and electrotherapy have shown to help alleviating post-operation complications and affect gait kinematics and muscle strength.Aim: This case study aimed to manage the post-operative complications in a patient with investigate excessive ankle stiffness with kinetics, kinematics and Electromyography (EMG) approach.Materials and Methods: A 41-year-old female with post-operation complications including decreased right ankle range of motion (ROM) and strength underwent a 12-week of IASTM and Electrotherapy. Gait analysis was performed before and after the intervention.Results: The results showed notable improvements in ankle 3-dimensional (3D) ROM, power, moment, velocity, cadence, step length, ground reaction force (GRF) and decreased stiffness, muscles activity, single and double support time. Ankle dorsiflexion ROM was not notably increased during gait.Conclusion: Findings suggest that a 12-week intervention of IASTM and electrotherapy can improve gait mechanics and reduce muscle activity in a patient with excessive ankle stiffness.

Background: The physical fitness is essential for wrestlers to perform successfully. The Tabata Protocol can be appropriate to develop these physical qualities.Aim: This study aims to investigate the effects of high-intensity interval training using “Tabata  protocol” on the physical fitness of teenage wrestlers.Material and Methods: 16 participants were randomly assigned to two groups of Tabata training (n=8) and the control group (n=8). All mentioned variables were measured before and after 4 weeks of the intervention. Tabata training group performed Tabata protocol in 2- 3 sets of 8 exercises with 20 sec of training and 10 sec of rest. The control group kept up their normal training routine during the same time. Physical fitness components were measured. The collected data were statistically analyzed by an independent t-test at a significance level of P>0.05.Results: Wrestlers in both groups significantly increased physical fitness components except flexibility (P<0.05). Tabata training was significantly more efficient in endurance of core muscle (P= 0.019, ES= 0.490) and upper body strength (P= 0.001, ES= 0.490) than control group (P<0.05). Also, results showed that for leg explosive power, only Tabata training had a positive effect (P= 0.026, ES=0.541).Conclusions: Our results suggest that wrestlers after Tabata protocol interventions can obtain better physical fitness, and event time benefits with more efficient performance and time-efficient manner compared with control group.

The purpose of this research is to design a framework for strategic innovation in sports businesses based on Grounded theory. Data was collected using interviews, which involved 19 participants including sports management professors, sports business owners, as well as sports managers. Based on Grounded theory, 156 open codes, 18 substantive codes, and 6 theoretical codes were identified. The factors affecting strategic innovation in sports businesses included institutional factors (culture, institutions, and laws), innovative human resources (providing innovative ideas, recognizing innovative opportunities, and strategic thinking), knowledge of the team and business environment (team, market, and macroeconomics), infrastructure (education, technology, and university-industry connection), and management of innovative business processes (marketing research, branding, empowerment, and human resource capability). The development of strategic innovation in sports businesses is a topic that has received less attention, and understanding the factors affecting it can provide the basis for promoting and developing the innovation ecosystem in sports.