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Background: Caffeine is widely recognized as a potent ergogenic aid commonly used to enhance exercise performance and recovery. However, individual responses to caffeine can vary significantly, a variability that might be explained by genetic differences.Aim: This study aimed to investigate the influence of the CYP1A2 rs762551 SNP on the effects of caffeine (CAF) consumption on growth hormone (GH) and testosterone (TS) levels response to resistance exercise (RE) in male athletes.Materials and Methods: Thirty resistance-trained men (mean age 21.72±4.06 years, weight 77.31±14.07 kg, height 179.31±5.08 cm) participated in a randomized, double-blind, placebo-controlled, crossover study. They consumed either CAF (6 mg/kg) or placebo (PL; 6 mg/kg maltodextrin) one hour before performing a RE protocol including three sets with 85% of 1RM and two-minute rest. CYP1A2 genotyping categorized participants as AA homozygous ("fast" metabolizers) or AC heterozygous ("slow" metabolizers). GH and TS levels were measured by ELISA methods.Results: Repeated measures ANOVA showed significant differences in GH levels across time (F=10.94, P=0.000), with significant time-group (F=4.3, P=0.019) and time-genotype-group interactions (F=3.83, P=0.024). One-way ANOVA indicated significant differences in GH levels between CAF and PL conditions in AA individuals, but not in AC/CC genotypes. For testosterone, significant effects of time (F=14.88, P=0.000) and time-group interaction (F=3.197, P=0.045) were observed. Post-RE CAF supplementation significantly increased serum GH and TS levels in AA individuals compared to PL. Both CAF and PL groups showed increased serum hormone concentrations post-exercise.Conclusion: In conclusion, the study demonstrated that caffeine consumption significantly increased serum levels of growth hormone and testosterone in individuals with the AA genotype of the CYP1A2 rs762551 SNP. These findings suggest that genetic variations play a role in the hormonal response to caffeine, which may have implications for exercise performance and recovery strategies.

The present study investigated the effect of eight weeks of training with a gyroscope on identifying the body position in space, the semi-dynamic balance on the ground, and Huber's device score. Two groups of 30 Air Force (IRIAF) pilots with an average age of 27 years, height of 178, and weight of 80 kg were randomly assigned to two training and control groups. The training group was exposed to eight weeks of training with the gyroscope device. The pre-test and post-test of the two groups were compared using videography, star test, and Huber's score using the statistical method of repeated measurement. In the gyro test, there was no significant difference in the detection angle of the body position in the air in any groups before and after the test. However, an increase in rotation speed was observed in the training group. In Huber's test, there was no significant change in the control group before and after. However, in the training group, an improvement in the score was observed, especially in the non-superior limb, as well as a decrease in the difference in the score between the two hands. Stars were not observed in any groups before or after the test. According to the results, it can be concluded that despite the non-significance of the difference in the subjects' ejection angle and position identification in the training group, it occurred simultaneously as the rotation speed increased

Purpose: The aim of this study was to investigate the effect of 8-weeks endurance training on volume and capacity of lungs (forced expiratory volume in 1second, Forced vital capacity, ratio FEV1/FVC) and its relationship with BMI in Male Smoking students. Method: In order to accomplish this research 20 cigarette addicted men students referred to the smoking cessation clinic were randomly selected and were divided into two groups of experimental (n=10) (age: 15.33 ± 2.07 years and BMI: 25.41 ± 3.55 kg/m2) and the control group (n = 10) (age: 15.10 ± 2.81 years and BMI: 27.26 ± 66 kg/m2). The Spirometry indexes (FEV1/FVC, FEV1, FVC), height and weight were measured Prior and after 8-weeks of endurance training. Experimental group performed 8-weeks of progressive endurance training (3 sessions per week, 60 minutes per session) which included running with the intensity of 75% MHR. Intensity of exercise was controlled by maximum heart rate and the formula of (220-age) and the intensity level and duration of exercises increased in each session. Data analysis was done by using the variance analysis method for repetitive data and the independent T-test. Results: The results of this study showed that after eight weeks of endurance training, Spirometry indexes (FEV1/FVC, FEV1, FVC) significantly increased (P<0.05), and this increase had a negative relation with BMI (P<0.05, r=-0.62). Conclusion: the study showed that eight weeks of moderate-intensity endurance training improved volume and lung capacity of Male Smoking students and it could partly remove the damaging effects of smoking on physical and psychological health and it can help them quit smoking as well.