Creatine Kinase

Purpose: The aim of this study was to investigate the acute effects of HIFT exercise, on creatine kinase (CK) and lactate dehydrogenase (LDH) in blood serum in overweight adult men. Method : Twenty-two untrained non-smoker overweight men (age, 42.9 ± 5.6 years; body mass, 94.2 ± 9.3 kg; body height, 178.9 ± 4.5 cm; and BMI, 29.04 ± 3.3 kg/m2) volunteered to participate in this study and performed a session of HIFT exercise with 80-85% HRmax consisting of three sets of 10 exercises. Blood samples were collected before and immediately after training to measure serum CK and LDH levels. Results: The HIFT protocol significantly increased serum CK (Pre: 114.6 U/L; Post: 124.3U/L; p< 0.05{t=-5.48, p=0.001}); Also, LDH had a significant increase (pre:213.4 U/L, post: 225.4U/L; p<0.05{t=-4.09, p=0.001}). Conclusion: It can be concluded that HIFT with AMRAP (as many repeats as possible) protocol will lead to a significant increase in some indicators of muscle damage such as CK and LDH levels in overweight men. This protocol can lead to muscle damage in overweight men.

Purpose: Delayed onset muscle soreness (DOMS) is pain and stiffness that occurs several hours to several days after unusual or intense exercise. It is thought that this exercise causes small damage (micro trauma) to muscle fibers. The aim of the present study was to compare the effects of high-intensity resistance training and resistance retraining on serum levels of some indices of muscle damage in inactive young girls. Method: Twenty-four healthy inactive young girls voluntarily participated in the present study. They then randomly divided into two groups of 10. The muscle injury protocol included five stations of biceps and shoulder presses with a barbell, squats, chest press, and leg press. Each movement consisted of three sets of 8 to 12 repetitions, with an intensity of 75% of one repetition maximum. Serum levels of creatine kinase, lactate dehydrogenase, and aspartate aminotransferase enzymes were measured before the activity and at intervals of 1, 26, and 48 hours after it. Analysis of variance with repeated measures and independent t-test were used to analyze the data at a significance level of p≥0.05. Results: there was no significant difference in the changes in creatine kinase, lactate dehydrogenase, and aspartate aminotransferase between the two groups at different stages of measurement after retraining (p<0.05). Conclusion: According to the results of the present study, it can be concluded that resistance training cannot be a significant influencing variable on the amount of muscle damage. However, more research in this field is needed.