The present study aimed to predict marital disaffection based on early maladaptive schemas with the mediation of cognitive emotion regulation in working women. This research was applied in terms of objective and correlational descriptive in terms of method, which was implemented using structural equation modeling. The statistical population of this research consisted of all working women studying in the Islamic Azad University of Karaj branch in the second semester of 2023-2024, and 308 of them were selected by available sampling method. The study tool included the Marital Disaffection Scale by Kayser (1996); the Young's Schema Questionnaire short version (1998) and the Cognitive Emotion Regulation Questionnaire by Garnefski et al.'s (2001). The structural equation modeling method was used to analyze the data. The results showed that marital disaffection is predicted based on early maladaptive schemas in working women (P=0.001, β=0.400). Marital disaffection is predicted based on maladaptive (p=0.001, β=0.449) and adaptive (p=0.001, β=-0.378) strategies of cognitive emotion regulation in working women. Marital disaffection is predicted based on based on early maladaptive schemas with the mediation of maladaptive (P=0.001, Z=4.11) and adaptive strategies (P=0.001, Z=3.73) cognitive regulation of emotion in working women.
